Gel Electrophoresis Reagents and Buffers
Cell Signaling Technology Color-coded Prestained Protein Marker, Low Range (1.7-42 kDa) 250 µl
Color-coded Prestained Protein Marker, Low Range (1.7-42 kDa) 250 µl
ABclonal Technology ETHE1 Rabbit pAb
This gene encodes a member of the metallo beta-lactamase family of iron-containing proteins involved in the mitochondrial sulfide oxidation pathway. The encoded protein catalyzes the oxidation of a persulfide substrate to sulfite. Certain mutations in this gene cause ethylmalonic encephalopathy, an infantile metabolic disorder affecting the brain, gastrointestinal tract and peripheral vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
ABclonal Technology ULBP1 Rabbit pAb
The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology ZNF471 Rabbit pAb
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus.
Sigma Aldrich Fine Chemicals Biosciences fluorescent IEf-Marker pI
FLUORESCENT fluorescent IEf-Marker pI
Sigma Aldrich Fine Chemicals Biosciences fluorescent IEf-Marker pI
filtered through a 0.45 mum membrane filter
ABclonal Technology KIF22 Rabbit pAb
The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology SGPL1 Rabbit pAb
Enables sphinganine-1-phosphate aldolase activity. Involved in apoptotic signaling pathway, fatty acid metabolic process, and sphingolipid metabolic process. Located in endoplasmic reticulum. Implicated in nephrotic syndrome type 14.
ABclonal Technology Cpsf4l Rabbit pAb
Predicted to be involved in pre-mRNA cleavage required for polyadenylation. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Is expressed in central nervous system and retina. Orthologous to human CPSF4L (cleavage and polyadenylation specific factor 4 like).
ABclonal Technology KAT5/Tip60 Rabbit pAb
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.
ABclonal Technology GNAT3 Rabbit pAb
Sweet, bitter, and umami tastes are transmitted from taste receptors by a specific guanine nucleotide binding protein. The protein encoded by this gene is the alpha subunit of this heterotrimeric G protein, which is found not only in the oral epithelium but also in gut tissues. Variations in this gene have been linked to metabolic syndrome.
ABclonal Technology ESPN Rabbit pAb
This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement.
ABclonal Technology XPNPEP3 Rabbit pAb
The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.
ABclonal Technology SHIP1 Rabbit pAb
This gene encodes a protein from the inositol polyphosphate-5-phosphatase (INPP5) family, containing an SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. It is expressed mainly in hematopoietic cells, where its translocation from the cytosol to the plasma membrane is regulated by tyrosine phosphorylation. At the plasma membrane, it hydrolyzes the 5 phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, influencing multiple signaling pathways. It also localizes to the nucleus, possibly participating in nuclear inositol phosphate signaling. The protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations are linked to immune system defects, cancers, and Inflammatory Bowel Diseases like Crohns and Ulcerative Colitis. Alternative splicing generates multiple transcript variants.